CREST News
Explore the latest research breakthroughs, collaborations, and accomplishments from the Center for Real-World Effectiveness & Safety of Therapeutics (CREST).
Publication
Dr. Carmen Guerra Co-Authors Updated American Cancer Society Colorectal Cancer Screening Guideline
July 20, 2026
Carmen E. Guerra is a co-author of the latest American Cancer Society colorectal cancer screening guideline, which introduces new screening options and updates recommendations for average-risk adults.
Publication
Sean Hennessy Co-Authors Publication on Improving Cardiovascular Risk Prediction Across Diverse Populations
July 13, 2026
Sean Hennessy, PharmD, PhD, co-authored a new publication examining limitations in current cardiovascular disease risk prediction methods and the need for more precise approaches to improve accuracy and equity across diverse populations.
In the Media
Dr. Charles Leonard Outlines Reforms to Align Energy Policy With Health Risks of Extreme Heat
May 13, 2026
In a new STAT First Opinion, Charles E. Leonard argues that access to air conditioning should be treated as essential preventive care as extreme heat increasingly threatens people living with chronic diseases.
Event
Save the Date: Workshop on Penn CFAR–PDPH Research Collaborations, March 17, 2026
January 5, 2026
Save the Date – March 17, 2026. Join Penn CFAR and the Philadelphia Department of Public Health for a workshop highlighting opportunities for collaborative HIV research and high-impact partnerships supporting Ending the HIV Epidemic in Philadelphia.
Publication
How Evidence-Based Advocacy is Shaping FDA Drug Labels
December 17, 2025
In a recent interview, Dr. Sean Hennessy highlights how scientific evidence and advocacy can drive FDA label changes that expand access to safe, effective medications.
Publication
National Medicaid Study Shows Rising Use of Methadone and Buprenorphine for OUD
December 1, 2025
Penn researchers have received NIH/NIBIB funding to develop robust and interpretable multi-modal AI models that integrate genomics, imaging, and electronic health data to advance cancer and Alzheimer’s disease research.
In the Media
Publication
Rising Temps, Rising Risks: How Climate Change Impacts Diabetes
February 19, 2025
Rising temperatures pose serious risks for people with type 2 diabetes, increasing the likelihood of heat exhaustion, blood sugar fluctuations, and cardiac issues. Charles Leonard, PharmD, MSCE, FISPE addresses these health threats with Yale Climate Connections.
Community Spotlight
Community Spotlight: Kacie Bogar, MS
October 1, 2024
For almost three years, Kacie Bogar, MS has served as a Research Project Manager for the Center for Real-World Effectiveness and Safety of Therapeutics (CREST) and the Epidemiology division in the Department of Biostatistics, Epidemiology and Informatics.